Cerebral Blood Flow and Oxygen Metabolism in Children with Hydrocephalus

  • Shirane R
  • Sato S
  • Kameyama M
  • et al.
N/ACitations
Citations of this article
2Readers
Mendeley users who have this article in their library.
Get full text

Abstract

In this study, we measured regional cerebral blood flow (rCBF) and the cerebral metabolic rate for oxygen (rCMRO 2 ), using positron emission tomography (PET) with O 15-radiopharmaceuticals, to clarify the pathophysiology of hydrocephalus in the developing brain. Seven hydrocephalic children without severe neurological deficit were studied. Hypoperfusion and lower rCMRO 2 values were observed in the prefrontal, parietal, and visual association cortices which surrounded the dilated anterior or posterior horns of the lateral ventricle. In those cases with markedly enlarged anterior or posterior horns, the surrounding cortices showed relatively lower rCMRO 2 values with the fall of rCBF. Hydrocephalus tended to damage various association cortices were functional development occurs later than in other cortical regions.

Cite

CITATION STYLE

APA

Shirane, R., Sato, S., Kameyama, M., Ogawa, A., Yoshimoto, T., Hatazawa, J., & Ito, M. (1991). Cerebral Blood Flow and Oxygen Metabolism in Children with Hydrocephalus. In Hydrocephalus (pp. 144–152). Springer Japan. https://doi.org/10.1007/978-4-431-68156-4_14

Register to see more suggestions

Mendeley helps you to discover research relevant for your work.

Already have an account?

Save time finding and organizing research with Mendeley

Sign up for free