Primary Non-Hodgkins lymphoma of the parotid gland

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Abstract

Primary malignant lymphomas in the salivary glands are relatively rare. Clinical presentation is not characteristic and the disease is often overlooked resulting in diagnosis and treatment delays. Aim: To stress the importance of the diagnostic process and combined management, we present a series of eight patients with malignant lymphoma of the parotid who were diagnosed only after surgery and managed with radiation and chemotherapy. Methods: Retrospective series of patients with primary malignant lymphoma of the parotid gland managed with radiotherapy and diagnostic surgical partial resection. Results: After treatment completion we achieved a loco-regional control rate of 87.5%. Toxicity was charted according to the Common Toxicity Criteria and it was seen in six patients (75%). Six patients are still alive without evidence of recurrent disease in their last follow-up. Conclusion: Our study confirms that primary early stage Non-Hodgkin Lymphoma of the parotid gland is a disease with an excellent prognosis and a good local control rate, with minimal morbidity.

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Dispenza, F., Cicero, G., Mortellaro, G., Marchese, D., Kulamarva, G., & Dispenza, C. (2011). Primary Non-Hodgkins lymphoma of the parotid gland. Brazilian Journal of Otorhinolaryngology, 77(5), 639–644. https://doi.org/10.1590/S1808-86942011000500017

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