Abstract
Quantitative systems pharmacology (QSP) has emerged as an innovative approach in model-informed drug discovery and development, supporting program decisions from exploratory research through late-stage clinical trials. In this commentary, we discuss the unique value of disease-scale “platform” QSP models that are amenable to reuse and repurposing to support diverse clinical decisions in ways distinct from other pharmacometrics strategies.
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CITATION STYLE
Musante, C. J., Ramanujan, S., Schmidt, B. J., Ghobrial, O. G., Lu, J., & Heatherington, A. C. (2017). Quantitative Systems Pharmacology: A Case for Disease Models. Clinical Pharmacology and Therapeutics, 101(1), 24–27. https://doi.org/10.1002/cpt.528
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