Diversity oriented design of various benzophenone derivatives and their in vitro antifungal and antibacterial activities

Abstract

A series of new substituted benzophenone derivatives was designed, synthesized and screened for their antifungal and antibacterial activities. The bioassays indicated that most of the synthesized compounds showed some antifungal activity against the tested phytopathogenic fungi, but lower antibacterial activities towards the five vibrios isolated from marine sources. The preliminary structure activity relationship (SAR) of the compounds was also discussed. © 2011 by the authors; licensee MDPI, Basel, Switzerland.