MR imaging features of Lhermitte-Duclos disease: Case reports and literature review

Abstract

Rationale:Lhermitte-Duclos disease (LDD) is a rare tumor of the nervous system with a typical "tiger striped'" sign, but its features on functional magnetic resonance imaging (fMRI) are still inconclusive.Patient concerns:To explore the characteristics of LDDs using fMRI.Diagnoses:We report 3 cases of pathologically confirmed LDDs.Interventions:Three patients underwent brain tumor surgery.Outcomes:All the patients had a good prognosis.Lessons:Magnetic resonance spectroscopy and susceptibility-weighted imaging combined with conventional MRI can be used to better diagnose LDDs. Perfusion-weighted imaging is not specific for distinguishing cerebellar tumors. The combined application of fMRI and conventional MRI can improve the accuracy of LDD diagnoses.