Interface of phospholipase activity, immune cell function, and atherosclerosis

N/ACitations
Citations of this article
26Readers
Mendeley users who have this article in their library.

Abstract

Phospholipases are a family of lipid-altering enzymes that can either reduce or increase bioactive lipid levels. Bioactive lipids elicit signaling responses, activate transcription factors, promote G-coupled-protein activity, and modulate membrane fluidity, which mediates cellular function. Phospholipases and the bioactive lipids they produce are important regulators of immune cell activity, dictating both pro-inflammatory and pro-resolving activity. During atherosclerosis, pro-inflammatory and pro-resolving activities govern atherosclerosis progression and regression, respectively. This review will look at the interface of phospholipase activity, immune cell function, and atherosclerosis.

Cite

CITATION STYLE

APA

Schilke, R. M., Blackburn, C. M. R., Bamgbose, T. T., & Woolard, M. D. (2020, October 1). Interface of phospholipase activity, immune cell function, and atherosclerosis. Biomolecules. MDPI AG. https://doi.org/10.3390/biom10101449

Register to see more suggestions

Mendeley helps you to discover research relevant for your work.

Already have an account?

Save time finding and organizing research with Mendeley

Sign up for free