Stereoselective 1,2- cis Glycosylation Reaction of 1- O -Acetylribose with Silylated Nucleophiles by the Promotion of a New Catalyst System

Abstract

1,2-cis-Ribofuranosides are stereoselectively prepared in high yields by the reaction of 1-O-acetyl-β-d-ribose with silylated nucleophiles by the promotion of a new catalyst system, the combined use of a catalytic amount of tin(IV) chloride and tin(II) triflate with a stoichiometric amount of lithium perchlorate.