Leiomyosarcoma of the uterus: Ultrasonography and serum lactate dehydrogenase level

45Citations
Citations of this article
11Readers
Mendeley users who have this article in their library.
Get full text

Abstract

Between January 1 1979, and September 30, 1990, a total of 1,886 patients in the National Defense Medical College Hospital, a self-referred population, had a hysterectomy because of signs and symptoms presumably resulting from uterine myomas. After hysterectomy with presumed benign disease, a histologic diagnosis of leiomyosarcoma was made in 7 patients (0.37%). Preoperative diagnosis of leiomyosarcoma was not made in any of the 7 patients. However, serum lactate dehydrogenase levels were abnormally elevated in 3 of them, and degenerative changes were found within the tumor by ultrasonography in 5 of them. Furthermore, increased lactate dehydrogenase levels and degenerative changes within the tumor were found in 3 of the patients whose tumors had 10 or more mitoses per 10 high-power fields. The prognosis for the leiomyosarcomas with increased mitotic rates is very poor. Therefore, a degenerative change within the uterine mass and an increased lactate dehydrogenase level, when present, should suggest the diagnosis of leiomyosarcoma. © 1992 S. Karger AG, Basel.

Cite

CITATION STYLE

APA

Seki, K., Hoshihara, T., & Nagata, I. (1992). Leiomyosarcoma of the uterus: Ultrasonography and serum lactate dehydrogenase level. Gynecologic and Obstetric Investigation, 33(2), 114–118. https://doi.org/10.1159/000294861

Register to see more suggestions

Mendeley helps you to discover research relevant for your work.

Already have an account?

Save time finding and organizing research with Mendeley

Sign up for free