Triterpenoids, steroid, and aromatic compounds from Combretum indicum leaves

Abstract

Combretum indicum belonging to the Combretaceae family possessed many bioactivities such as pain relief, antipyretic, antimicrobial, antioxidant, anticancer, etc. However, there had not much chemically studied on this species, especially, in Viet Nam. Herein, eight compounds consisting of asiatic acid (1), arjunolic acid (2), oleanolic acid (3), benzyl-β-D-xylopyranosyl-(1′′ → 6′)-β-D-glucopyranoside (4), nudifloric acid (5), vanillin (6), gallic acid (7), and β-sitosterol (8) were reported from the Combretum indicum leaves collected at Ho Chi Minh City, Viet Nam. Their chemical structures were elucidated by the MS and NMR spectroscopic analysis as well as the comparison of their NMR data with the published data. Compounds 1, 3, 4, 5, and 6 were notified for the first time from Combretum indicum.