Laboratory diagnostics for histoplasmosis

195Citations
Citations of this article
236Readers
Mendeley users who have this article in their library.

This article is free to access.

Abstract

The diagnosis of histoplasmosis is based on a multifaceted approach that includes clinical, radiographic, and laboratory evidence of disease. The gold standards for laboratory diagnosis include demonstration of yeast on pathological examination of tissue and isolation of the mold in the culture of clinical specimens; however, antigen detection has provided a rapid, noninvasive, and highly sensitive method for diagnosis and is a useful marker of treatment response. Molecular methods with improved sensitivity on clinical specimens are being developed but are not yet ready for widespread clinical use. This review synthesizes currently available laboratory diagnostics for histoplasmosis, with an emphasis on complexities of testing and performance in various clinical contexts.

Author supplied keywords

Cite

CITATION STYLE

APA

Azar, M. M., & Hage, C. A. (2017, June 1). Laboratory diagnostics for histoplasmosis. Journal of Clinical Microbiology. American Society for Microbiology. https://doi.org/10.1128/JCM.02430-16

Register to see more suggestions

Mendeley helps you to discover research relevant for your work.

Already have an account?

Save time finding and organizing research with Mendeley

Sign up for free