Angioimmunoblastic T‐cell lymphoma: a rare subtype of peripheral T‐cell lymphoma

Abstract

Angioimmunoblastic T‐cell lymphoma ( AITL ) is a rare form of NHL and usually presents in the late stage due to the atypical laboratory findings. Immunohistochemistry of the lymph node in AITL is characterized by positive CD 2, CD 3, CD 4, CD 10, CXCL ‐13, PD 1 often BCL ‐6 and CD 20 positive. Meshworks of follicular dendritic cells are seen outside follicles with CD 21 and CD 23 stains. EBV can be often positive as well. Autologous transplantation should be offered in the first remission as poor outcome is reported with anthracycline‐containing regimens.