STUDY TO ASSESS RELATION OF LIPID PROFILE AND HYPERTENSION IN PATIENTS ATTENDING NIMS HOSPITAL, JAIPUR, RAJASTHAN

Abstract

Dyslipidaemia and hypertension are major cardiovascular disease risk factors, and the Indian population experiences the highest rates of morbidity and mortality. The objective of this study was to determine the relation between lipid profiles in hypertensive patients with normotensive control subjects in patients attending NIMS Hospital, Jaipur Rajasthan. A single-Center, case-control hospital based study was carried out among 140 participants (eighty (80) patients were included in the study) from January 2021 to June 2022 in National Institute of Medical Sciences and Research, Jaipur, Rajasthan, India. Data were collected on sociodemographic factors, anthropometric measurements, blood pressure, and lipid profile including total cholesterol (TC), triglyceride (TG), low density lipoprotein (LDL), and high density lipoprotein (HDL). On analysis of the lipid profile of 80 hypertensive patients and 80 Normotensive control subjects the mean TC values in cases and controls are 199 mg/dl and 167 mg/dl respectively. The mean TG values are 199 mg/dl and 123 mg/dl, the mean LDL c values are 121.5 mg/dl and 97.5 mg/dl. The serum levels of TC, TG, and LDL were higher while HDL levels were lower in hypertensive subjects compared to normotensives, which was statistically significant (P<0.001). Age, waist circumference, and body mass index showed significant association with hypertensive patients (P<0.0001) but not with normotensives. The logistic regression analysis showed that hypertensive patients had higher TC and TG, LDL and lower HDL than normotensives, which was statistically significant (P<0.05). Hypertensive patients in NIMS hospital, Jaipur, Rajasthan have a close association with dyslipidaemia and need measurement of blood pressure and lipid profile at regular intervals to prevent cardiovascular disease, stroke, and other comorbidities.