A line probe assay (INNO-LiPA HBV DR) detecting drug-resistant hepatitis B virus (HBV) strains was evaluated. Results concordant with sequence analysis were obtained with 48 of 56 serum samples from HBV-infected patients undergoing lamivudine therapy. In eight cases, additional minor subpopulations could be identified by the line probe assay.
CITATION STYLE
Aberle, S. W., Kletzmayr, J., Watschinger, B., Schmied, B., Vetter, N., & Puchhammer-Stöckl, E. (2001). Comparison of sequence analysis and the INNO-LiPA HBV DR line probe assay for detection of lamivudine-resistant hepatitis B virus strains in patients under various clinical conditions. Journal of Clinical Microbiology, 39(5), 1972–1974. https://doi.org/10.1128/JCM.39.5.1972-1974.2001
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