Neurogenesis in adult brain

0Citations
Citations of this article
121Readers
Mendeley users who have this article in their library.
Get full text

Abstract

Brain injuries of any etiology including traumatic injuries, neurodegenerative diseases or strokes are very common and involve irreversible impairments in cognitive function, motor and somatosensory system, and even personality. These types of lesions lack effective curative treatments, with the search for therapeutic options being one of the most active fields of research in current neuroscience. In this sense, the discovery of neural replenishment from neural stem cells (NSC) in the adult central nervous system (CNS) has been a new approach in the development of therapies for this type of brain injury. The discovery of neural stem cells (NSCs) in the adult brain has opened up the possibility of developing new neuroregenerative therapies based on neural replenishment from neural stem cells (neurogenesis). In physiological conditions, neurogenesis exists from NSC only in two areas of the adult brain, the hippocampus and the subventricular zone (SVZ), whereas in the rest of the adult brain there is no or little neurogenesis. However, when a brain injury occurs, these NSCs are recruited into the perimeter of the lesion and cells with proliferating neural precursor (NPC) characteristics can be seen. The publication provides a comprehensive review of current knowledge on neurogenesis in adult brain.

Cite

CITATION STYLE

APA

Navarro-Quiroz, E., Navarro-Quiroz, R., España-Puccini, P., Ahmad, M., Díaz-Pérez, A., Villarreal, J. L., … Torres, A. (2018, January 1). Neurogenesis in adult brain. Salud Uninorte. Universidad del Norte. https://doi.org/10.14482/sun.34.1.9992

Register to see more suggestions

Mendeley helps you to discover research relevant for your work.

Already have an account?

Save time finding and organizing research with Mendeley

Sign up for free