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Passive vs. Active Targeting: An Update of the EPR Role in Drug Delivery to Tumors

  • Upponi J
  • Torchilin V
DOI: 10.1007/978-3-319-08084-0_1
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Abstract

A variety of active pharmaceutical ingredients (APIs) currently used for cancer treatment are cytotoxic, and show nonspecific distribution when administered systemically resulting in toxicity to normal tissues, hence limiting their clinical application. To overcome...

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Upponi, J. R., & Torchilin, V. P. (2014). Passive vs. Active Targeting: An Update of the EPR Role in Drug Delivery to Tumors (pp. 3–45). https://doi.org/10.1007/978-3-319-08084-0_1

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