A continuous-time markov chain modeling cancer-immune system interactions

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Abstract

In the present paper we propose two mathematical models describing, respectively at the microscopic level and at the mesoscopic level, a system of interacting tumor cells and cells of the immune system. The microscopic model is in terms of a Markov chain defined by the generator, the mesoscopic model is developed in the framework of the kinetic theory of active particles. The main result is to prove the transition from the microscopic to mesoscopic level of description.

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Burini, D., De Angelis, E., & Lachowicz, M. (2018). A continuous-time markov chain modeling cancer-immune system interactions. Communications in Applied and Industrial Mathematics, 9(2), 106–118. https://doi.org/10.2478/caim-2018-0018

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