Versatile amine-promoted mild methanolysis of 3,5-dinitrobenzoates and its application to the synthesis of Colorado potato beetle pheromone

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Abstract

A mild deacylation method for 3,5-dinitrobenzoates using methanolic solutions of amines, such as dialkylamines, was developed. The method’s versatility was confirmed by applying it to synthesizing a key intermediate for Colorado potato beetle pheromone.

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Yamano, Y., Sasaki, H., & Wada, A. (2017). Versatile amine-promoted mild methanolysis of 3,5-dinitrobenzoates and its application to the synthesis of Colorado potato beetle pheromone. Chemical and Pharmaceutical Bulletin, 65(10), 940–944. https://doi.org/10.1248/cpb.c17-00462

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