Hippocampal, Subicular, and Entorhinal Afferents and Synaptic Integration in Rodent Cingulate Cortex

Abstract

There is now compelling evidence, based on studies in many species and laboratories, that cingulate cortex is one of the important targets of the hippocampal formation. Source structures include the hippocampus, subicular complex, and entorhinal cortex. Using new anatomical tract tracing techniques, several reports published in the late 1970s added considerably to our understanding of hippocampal formation outputs and showed that several tenets of hippocampal organization required revision. For years, the principal hippocampal outputs were regarded as subcortical projections via the fornix system. The subiculum, though well described by Lorente de Nó using the Golgi technique (Lorente de Nó, 1933), was usually ignored.