Synthesis and Characterization of Hydrogels Cross-Linked with Gamma Radiation for Use as Wound Dressings

Abstract

In this work, the synthesis of cross-linked PVA/PVP 10% w/v hydrogels was carried out by using ionizing energy at a dose of 30 kGy from a Co60 source in order to be used as dressings for skin wounds. These hydrogels were characterized by various tests such as swelling, dehydration, surface pH, Fourier Transform Spectroscopy (FTIR), Scanning Electron Microscopy (SEM) and Cytotoxicity. The results of these tests allowed us to evaluate the physical, chemical and biological properties of these and ensure that these hydrogels are a good tool for the treatment of skin burns.