Sangue periférico como fonte de células para terapia cellular

Abstract

Peripheral blood has been routinely used as a source of hematopoietic progenitor cells for allogeneic and autologous bone marrow transplantation. Recent studies have demonstrated that alow number of mesenchymal stem cells are also present in the peripheral blood. They share the same surface markers as bone marrow-derived mesenchymal stem cells and are capable of differentiating into mesenchymal lineage cells including osteocytes, adipocytes and chondrocytes. Although their origin and destination are unclear, their presence in the peripheral blood of adults seems to represent an important and powerful tool for regenerative medicine and cell therapy.