Anti-diabetic Effects of Basil Extract (Ocimum Basilicum) towards Hyeperglycemia in Gestational Diabetes Mellitus

Abstract

Gestational Diabetes Mellitus is a disorder of carbohydrate tolerance that occurs or firstly known during pregnancy. Basil (Ocimum Basilicum) was reported as an herbal plant that contains active substances as antidiabetic drugs. This study aims at the antidiabetic effect of basil extract (ocimum basilicum) towards hyperglycemia in gestational diabetes mellitus. The research sample was carried out on 24 pregnant rats that induced streptozotosin 40 mg / kg BW. Samples were divided into 4 groups: negative control, positive control induced by streptozotosin, and 2 treatment groups induced by streptozotosin and given basil extract with doses of 100 mg / kg BW and 200 mg / kg BW. Examination of blood glucose using a blood glucometer. From the results of this study, p value < 0,05 which means it was concluded that there was an effect of basil extract on the decrease in blood glucose.