Condensation of the anilide of acetoacetic acid, thiophene aldehyde, cyanothioacetamide and N-methylmorpholine gave N-methylmorpholinium 6-methyl-4-(2-thienyl)-5-phenylcarbamoyl-3-cyano-1,4-dihydropyridine-2-thiolate which reacted with various halides ZCH2Hal or H2NCOCH(Ph)Cl to give substituted 2-ZCH2-thio or 2-H2NCOCH(Ph)-thio-1,4-dihydropyridines. ©1997 Plenum Publishing Corporation.
CITATION STYLE
Dyachenko, V. D., Krivokolysko, S. G., & Litvinov, V. P. (1997). Synthesis of N-methylmorpholinium 6-methyl-4-(2-thienyl)-5-phenylcarbamoyl-3-cyano-1,4-dihydropyridine-2-thiolate and its reaction with various functionally substituted methyl halides. Chemistry of Heterocyclic Compounds, 33(5), 577–582. https://doi.org/10.1007/BF02291942
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