We analyzed the staphylococcal cassette chromosome mec (SCCmec) types of 143 fusidic acid- and methicillin-resistant Staphylococcus epidermidis isolates. The most frequent SCCmec type was SCCmec III/SCCHg (53%), followed by SCCmec IV (29%). Clonal spreading of SCCmec III/SCCHg strains contributed to the increased prevalence of SCCmec III. A novel non-mec SCC structure, SCC7684, adjacent to SCCmec III, which carries a new ccrC allotype (ccrC3 allele 1) and contains heavy metal resistance genes, was identified in 14 isolates.
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Chen, H. J., Lin, Y. T., Hung, W. C., Tsai, J. C., Hsueh, P. R., & Teng, L. J. (2016). Distribution of Staphylococcal Cassette Chromosome (SCC) mec element types in fusidic acid-resistant Staphylococcus epidermidis and identification of a novel SCC7684 element. Antimicrobial Agents and Chemotherapy, 60(8), 5006–5009. https://doi.org/10.1128/AAC.00231-16