Anti-candida and anti-quorum sensing activity of airborne microorganisms detected by a rapid method

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Abstract

Introduction: Introducing new antibiotics to the clinic is critical. Methods: We adapted a plate method described by Kawaguchi and coworkers in 2013 1 for detecting inhibitory airborne microorganisms. Results: We obtained 51 microbial colonies antagonist to Chromobacterium violaceum, purified and retested them, and of these, 39 (76.5%) were confirmed. They comprised 24 bacteria, 13 fungi, and 2 yeasts. Among the fungi, eight (61.5%) produced active extracts. Among the bacterial, yeast, and fungal strains, 17 (44.7%) and 12 (31.6%) were active against Candida albicans and Candida parapsilosis, respectively. Conclusions: The proposed screening method is a rapid strategy for discovering potential antibiotic producers.

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Cruz, A. L., de Souza, F. S., & Abegg, M. A. (2019). Anti-candida and anti-quorum sensing activity of airborne microorganisms detected by a rapid method. Revista Da Sociedade Brasileira de Medicina Tropical, 52. https://doi.org/10.1590/0037-8682-0152-2018

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