Reconstruction of central blood pressure using an individualized two-segment transmission line model

Abstract

This paper proposes a method to reconstruct the aortic blood pressure (BP) waveform from the radial BP waveform using an individualized model which is based on individualizing pulse transit time (PTT). In this method, the upper-limb arterial branch is characterized by two segments of transmission line (TL) in series. This method was tested on 8 simulated subjects using the leave-one-out cross-validation method. The results of the synthetic experiment demonstrated that the individualized model can reconstruct the central BP waveform correctly and outperformed the generalized model.