Red cell distribution width and platelet indices as predictors in determining the prognosis of upper gastrointestinal system bleeding

Abstract

Background and Aim: Acute upper gastrointestinal bleeding (AUGIB) is one of the most common medical emergencies. Early detection of at-risk patients is beneficial with respect to treatment and prognosis. We investigated whether severity of ulcers were associated with red blood cell distribution width (RDW), plateletcrit (PCT), mean platelet volume (MPV) and platelet distribution width (PDW). Materials and Methods: All patients presenting to the emergency department with AUGIB between January 2014 and December 2017 were included in the study. Endoscopy reports, complete blood counts, patient demographic characteristics, and endoscopy results were obtained retrospectively from hospital records. Patients with grade I or grade II ulcers (based on the Forrest classification) were compared in regard to these parameters. Results: In total, 373 male and 211 female patients with a mean age ± SD of 66.36 ± 17.36 were included in this study. Ulcers were detected in 396 of 584 patients (67.8%). There were no differences with respect to RDW or platelet indices between groups. Conclusions: Patients presenting with AUGIB should receive rapid diagnosis and treatment. In this study of patients with AUGIB grouped by bleeding aetiology, probable early prognostic parameters were not associated with bleeding severity among patients diagnosed with gastric or duodenal ulcers.