Double-blind placebo-controlled studies often include two parallel groups receiving different treatment modalities. Unlike crossover studies (Chap. 3), they involve independent treatment effects, i.e., with a zero correlation between the treatments. The two samples t-test, otherwise called the independent samples t-test or unpaired samples t-test, is appropriate for analysis.
CITATION STYLE
Cleophas, T. J., & Zwinderman, A. H. (2016). Unpaired Continuous Data (Unpaired T-Test, Mann-Whitney). In Clinical Data Analysis on a Pocket Calculator (pp. 37–43). Springer International Publishing. https://doi.org/10.1007/978-3-319-27104-0_7
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