Tractometer: Online evaluation system for tractography

Abstract

We have developed a Tractometer: an online evaluation system for tractography processing pipelines. One can now evaluate the end effects on fiber tracts of different acquisition parameters (b-value, number of directions, denoising or not, averaging or not), different local estimation techniques (tensor, q-ball, spherical deconvolution, spherical wavelets) and to different tractography parameters (masking, seeding, stopping criteria). At this stage, the system is solely based on a revised FiberCup analysis, but we hope that the community gets involved and provides us with new phantoms, new algorithms, third party libraries and new geometrical metrics, to name a few. We believe that the new connectivity analysis and tractography characteristics proposed can highlight limits of the algorithms and contribute in elucidating the open questions in fiber tracking: from raw data to connectivity analysis.