Roles of BRAHMA and its interacting partners in plant chromatin remodeling

Abstract

Chromatin remodeling represents a dynamic change of open or closed chromatin structure, which is closely related to the transcriptional regulation. The regulation by the Switch/Sucrose non-fermenting (SWI/SNF) chromatin remodeling complex is crucial for embryonic, vegetative, and reproductive development. A catalytic ATPase of the SWI/SNF complex, BRAHMA (BRM), is evolutionarily conserved among eukaryotes. We focus on the role of plant BRM in the regulation of gene expression by altering the accessibility of the target DNA. We also introduce the interacting partners required for the recruitment of BRM to the target loci.