Immobilisation and Biosensors

Abstract

Immobilisation is defined as the technique of fixing the cells, organelles or enzymes/other proteins (monoclonal antibodies) onto a solid support system, into a solid support matrix or retained by a membrane, in order to maintain stability and make possible their repeated or continued use. The immobilised cell technologies comprise of modifications of the technique developed for enzymes. However the microbial size has a significant impact on these techniques. The immobilisation of microbial cells occurs as a natural phenomenon or through artificial process. The artificially immobilised cells are allowed restricted growth.