Specific detection of hypochlorite: a cyanine based turn-on fluorescent sensor

Abstract

Abstract: Judiciously designed cyanine based fluorogenic probe (L) can exhibit interesting solvent polarity induced isomerization. The probe displayed a highly selective TURN-ON fluorescence response towards hypochlorite among various reactive oxygen species (ROS) and analytes in a mixed aqueous medium. The sensing process was attributed to the formation of a probe-OCl adduct which results in restricting the donor-acceptor extended conjugation. The detection limit was found to be as low as 3 μ M. The proposed sensing mechanism is supported by mass spectrometric analysis and HPLC study. Graphical abstract: Cyanine based fluorogenic probe (L) selectively detect hypochlorite among various ROS with a detection limit of 3 μ M in mixed aqueous medium through TURN-ON fluorescence response. [Figure not available: see fulltext.].