Length does matter for cGAS

Abstract

In this study, we developed a novel method for a fullyautomatic segmentation and quantification of myocardialinfarction from delay enhancement - magnetic resonanceimaging. Hyper-enhanced region corresponding to the infarctcore is separated from normal tissue via a Gaussian mixturemodel. Then, peri-infarct area is determined by spatial-weightedfuzzy clustering. No-reflow area inside the infarct core is alsodefined by an improved thresholding. Results of quantificationare presented in per-slice and global volumetric analysis, as wellas in bull's eye of 16-segment model. Promising results have beenachieved in quantification and segmentation of myocardialinfarct. Our software could be used in clinical practice after acomplete validation.