Abstract
A DNA sequence situated in the human genome between Alu-repeat clusters ("Inter-Alu" DNA) is progressively amplified in extrachromosomal DNA, including covalently closed DNA circles, during serial passage of diploid fibroblasts. A single size-class of Inter-Alu circles is also amplified in lymphocytes from 16 of 24 old donors and yet is not detected in cells from 18 young donors.
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CITATION STYLE
APA
Lumpkin, C. K., McGill, J. R., Riabowol, K. T., Moerman, E. J., Reis, R. J., & Goldstein, S. (1985). Extrachromosomal circular DNA and aging cells. Advances in Experimental Medicine and Biology, 190, 479–493. https://doi.org/10.1007/978-1-4684-7853-2_24
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