Skip to main content
ArticleOPEN ACCESS

CTLA-4 blockade synergizes with cryoablation to mediate tumor rejection

OncoImmunology
DOI: 10.4161/onci.19442
30Citations
Citations of this article
42Readers
Mendeley users who have this article in their library.

This article is free to access.

Abstract

We report that cryoablation of primary tumors synergizes with anti-CTLA-4 treatment to mediate rejection of secondary tumors in the TRAMP mouse model of prostate cancer. T cells, in particular CD8+ T cells specific for the TRAMP antigen SPAS-1, were enriched in both secondary tumors and spleens of combination-treated mice. © 2012 Landes Bioscience.

Author supplied keywords

Cite

CITATION STYLE

APA

Waitz, R., Fassò, M., & Allison, J. P. (2012). CTLA-4 blockade synergizes with cryoablation to mediate tumor rejection. OncoImmunology. https://doi.org/10.4161/onci.19442

Register to see more suggestions

Mendeley helps you to discover research relevant for your work.

Already have an account?

Save time finding and organizing research with Mendeley

Sign up for free