Fast and fully automatic calibration of frequency offset for balanced steady-state free precession cardiovascular magnetic resonance at 3.0 Tesla

Abstract

Background: This study proposed a fast and fully automatic calibration system to suppress the dark banding artifacts in balanced steady-state free precession (bSSFP) cardiovascular magnetic resonance (CMR) at 3.0 T. Methods. Twenty-one healthy volunteers (18 men, 3 women; mean age 24.9 years) participated in this study after providing institutionally approved consent. The optimal frequency was obtained using sweep scans of transition-band low flip-angle bSSFP (bSSFP-L), performed with three conditions: breath-hold plus electrocardiography (ECG) triggering (BH + ECG), breath-hold only (BH), and free breathing (FB). A real-time feedback system was implemented to allow the performing of bSSFP-L calibration scanning and conventional cine bSSFP within one breath-hold. For each scan condition, the optimal phase was estimated using 20-point and 10-point spline fitting. Results: Linear regression analysis indicated high correlation between the optimal phases obtained using BH and FB and those obtained using BH + ECG (R§ssup§2§esup§ = 0.91 to 0.98, n = 21). The optimal phases obtained using 10-point datasets showed high correlation with the 20-point BH + ECG datasets (R§ssup§2§ esup§ = 0.92 to 0.99, n = 21); although the within-subject coefficient of variation (wsCV) was larger using 10-point fitting. The variation of repeated measurements was largest with FB acquisition and smallest with BH + ECG acquisition. The optimal frequency obtained by offline calculation and by real-time feedback calibration significantly reduced dark-band artifacts in cine bSSFP images (both p