Chromatographic Analysis of Water and Wine Samples for Phenolic Compounds Released from Food-Contact Epoxy Resins

Abstract

Food-contact epoxy resins can release phenolic compounds such as phenol, m-cresol, bisphenol F, bisphenol A, 4-tert-butylphenol, bisphenol F diglycidyl ether (BFDGE), and bisphenol A diglycidyl ether (BADGE) into foodstuffs. A validated high-performance liquid Chromatographic method with fluorometric detection is described for the simultaneous analysis of these compounds in wine and mineral water. Sample preparation by solid-liquid extraction enables detection limits of 2.5 μg/L in wine and 0.25 μg/L in mineral water to be achieved. Recovery rates are close to 100%, except for BFDGE and BADGE (around 60% in wine and 75% in mineral water).