Posterior reversible encephalopathy syndrome: An uncommon presentation of celiac disease

Abstract

Celiac disease is an autoimmune induced inflammatory disease of small intestine in genetically susceptible individuals by ingestion of gluten. Clinical manifestation of celiac disease is mostly gastrointestinal or atypical non-gastrointestinal symptoms or silent with no symptoms, despite the presence of a characteristic intestinal lesion. Wider spectrum of atypical symptoms include neurological syndrome like migraine, encephalopathy, mylopathy, neuropathy with positive antiganglioside antibodies and symptoms of osteomalacia. Autoimmune disorders occur ten times more frequently in adult patients with celiac disease than in the general population such as thyroid disease, type1 diabetes and Addison's disease etc. If celiac disease remains unrecognized, it can increase the risk of life-threatening complications that are difficult to manage. Herein we are presenting a case of posterior reversible encephalopathy, presenting in department of medicine with seizures. Patient was a diagnosed case of celiac disease.