Adequacy of Disease Control by Supraomohyoid Neck Dissection in cT1/T2 Tongue Cancer

3Citations
Citations of this article
6Readers
Mendeley users who have this article in their library.

Abstract

Background: Patients affected by oral tongue squamous cell carcinoma (OTSCC) underwent a supraomohyoid neck dissection (SOHND) or modified radical neck dissection (mRND) according to the clinical nodal status (cN0 vs. cN+). We investigate whether the type of neck dissection affects survival with the presence of extranodal extension (ENE) and multiple nodal metastases (MNM). Methods: We conducted a retrospective study enrolling surgically treated patients affected by cT1/T2 OTSCC and MNM or ENE. The outcomes assessed were: overall survival (OS), disease-free survival (DFS), and neck-control- and metastases-free survival (NC-MFS). Survival curves were plotted by the Kaplan–Meier method and the log-rank test. Furthermore, we conducted a multivariable analysis with the Cox regression model. Results: We included a total of 565 patients (36% cT1, 64% cT2). Of these, 501 patients underwent a SOHND, and 64 underwent an mRND. A total of 184 patients presented rpN+, with 28.7% of these in the SOHND group and 62.5% of these in the mRND group. We identified no significant differences in OS, DFS, and NC-MFS in the whole pN+ cohort, in the MNM, and the ENE subgroups. In the multivariable analysis, the type of ND did not affect OS and DFS. Conclusions: Treating cT1-2 N0/+ tongue cancer with SOHND is oncologically safe. ENE and MNM patients do not benefit from an mRND.

References Powered by Scopus

Elective versus therapeutic neck dissection in node-negative oral cancer

918Citations
N/AReaders
Get full text

Head and Neck Squamous Cell Carcinoma: Update on Epidemiology, Diagnosis, and Treatment

894Citations
N/AReaders
Get full text

Distribution of cervical lymph node metastases from squamous cell carcinoma of the upper respiratory and digestive tracts

827Citations
N/AReaders
Get full text

Cited by Powered by Scopus

The Role of Peritumoral Depapillation and Its Impact on Narrow-Band Imaging in Oral Tongue Squamous Cell Carcinoma

4Citations
N/AReaders
Get full text

A Study of the Prognostic Factors for Late Cervical Lymph Node Metastasis and Distant Metastasis in Patients with cT1-2N0 Tongue Cancer

3Citations
N/AReaders
Get full text

Can High-Frequency Intraoral Ultrasound Predict Histological Risk Factors in Oral Squamous Cell Carcinoma? A Preliminary Experience

3Citations
N/AReaders
Get full text

Register to see more suggestions

Mendeley helps you to discover research relevant for your work.

Already have an account?

Cite

CITATION STYLE

APA

Iandelli, A., Marchi, F., Chen, A. C., Young, C. K., Liao, C. T., Tsao, C. K., … Huang, S. F. (2022). Adequacy of Disease Control by Supraomohyoid Neck Dissection in cT1/T2 Tongue Cancer. Journal of Personalized Medicine, 12(9). https://doi.org/10.3390/jpm12091535

Readers' Seniority

Tooltip

Researcher 1

100%

Readers' Discipline

Tooltip

Medicine and Dentistry 2

100%

Save time finding and organizing research with Mendeley

Sign up for free