Melatonergic drugs and their therapeutic use in nasal polyposis

Abstract

Nasal polyposis is a common, chronic, and inflammatory disease of the mucous membranes of the nose and paranasal sinuses. The overall prevalence of rate ranges from 1 to 4 %. This chronic condition is characterized by edematous aggregates of inflamed mucosa prolapsing into the nose. The formation of nasal polyposis may lead to nasal airway obstruction, loss of smell, headache, increased secretion, and also a reduced quality of life.