New concepts for primary and secondary hyperparathyroidism

Abstract

Primary hyperparathyroidism and secondary disease from chronic kidney disease are highlighted in this chapter. Up-to-date descriptions of new pathological mechanisms focus on fibroblastic growth factor 23 and its emergent importance in overall pathology. Historical, clinical, and examination findings are highlighted and compliment data on laboratory techniques, diagnostic imaging, and skeletal histology clinical workup of the patients. Treatment options at the dialysis and pharmacological levels are blended with some of the nutritional elements in phosphorus control. The integration of all elements is summarized at the end of the section to emphasize its influence on bone metabolism.