Malignant melanoma and rubeosis iridis: Histopathological and statistical study

Abstract

308 cases of malignant melanoma of the uvea included 46 with rubeosis iridis. The occurrence of rubeosis correlated with increased tumour size, involvement of the anterior choroid, tumour necrosis, extensive retinal detachment, and an increased incidence of uveitis. No relationship was found between rubeo,is and extraocular tumour spread, cell type, or site of tumour origin. The incidence of the overall findings is compared with that of other series and the pathogenesis of rubeosis is discussed.