Mass spectrometry is a method of choice for quantifying low-abundance proteins and peptides in many biological studies. Here, we describe a range of computational aspects of protein and peptide quantitation, including methods for finding and integrating mass spectrometric peptide peaks, and detecting interference to obtain a robust measure of the amount of proteins present in samples.
CITATION STYLE
Zhang, G., Ueberheide, B. M., Waldemarson, S., Myung, S., Molloy, K., Eriksson, J., … Fenyö, D. (2010). Protein quantitation using mass spectrometry. Methods in Molecular Biology (Clifton, N.J.), 673, 211–222. https://doi.org/10.1007/978-1-60761-842-3_13
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