A planar bilayer lipid membrane sensor using a miniaturized auto-patch system

Abstract

A bilayer lipid membrane sensor was constructed with a miniaturized auto-patch system. The performance of the patch system was optimized to obtain an analytically relevant signal. A biosensor based on an anti-BSA-antibody as a receptor and gramicidin as a signal transduction element was demonstrated. The sensor for BSA exhibited a detection limit of pg/mL level for BSA.