Cutaneous and visceral chronic granulomatous disease triggered by a rubella virus vaccine strain in children with primary immunodeficiencies

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Abstract

Persistence of rubella live vaccine has been associated with chronic skin granuloma in 3 children with primary immunodeficiency. We describe 6 additional children with these findings, including 1 with visceral extension to the spleen.

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Neven, B., Pérot, P., Bruneau, J., Pasquet, M., Ramirez, M., Diana, J. S., … Eloit, M. (2017). Cutaneous and visceral chronic granulomatous disease triggered by a rubella virus vaccine strain in children with primary immunodeficiencies. Clinical Infectious Diseases, 64(1), 83–86. https://doi.org/10.1093/cid/ciw675

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