Intraepidermal Glandular Carcinoma of the Nipple (Mammary Paget-like Disease) in 2 Dogs

Abstract

Mammary Paget disease, characterized by diffuse infiltration of the nipple and areolar epidermis by carcinoma cells, develops in 1% to 3% of human mammary carcinomas. The purpose of this article is to present 2 cases of intraepidermal adenocarcinoma that resembled human mammary Paget disease, histologically and immunohistochemically, in dogs with underlying mammary carcinoma. © The Author(s) 2012.