Fitting and Statistical Analysis of Single-Channel Records

  • Colquhoun D
  • Sigworth F
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Abstract

The aims of analysis of single-channel records can be considered in two categories. The first is to allow one to observe results at leisure in order to determine their qualitative features. It may, for example, be found that the single-channel currents were not all of the same amplitude or that they showed obvious grouping into bursts or that artifacts appeared on the record that might be misleading. These effects are often not easy to see on the oscilloscope screen as an experiment proceeds. It is best to have a computer program that allows one, after the experiment, to scroll flexibly through the recorded data and zoom in on portions of the record to observe details at high time resolution.

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Colquhoun, D., & Sigworth, F. J. (1995). Fitting and Statistical Analysis of Single-Channel Records. In Single-Channel Recording (pp. 483–587). Springer US. https://doi.org/10.1007/978-1-4419-1229-9_19

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