Abstract
Background: The role of DAXX in ovarian cancer development and metastasis has not been investigated before now. Results: Overexpression of DAXX enhanced ovarian cancer cell proliferation, colony formation, and migration, whereas Daxx depletion had the opposite effects. Conclusion: DAXX promotes ovarian cancer cell proliferation and chemoresistance. Significance: ModulatingDAXXmay be an effective strategy for preventing the recurrence and chemoresistance of ovarian cancers. Copyright © 2013 by The American Society for Biochemistry and Molecular Biology, Inc.
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CITATION STYLE
Pan, W. W., Zhou, J. J., Liu, X. M., Xu, Y., Guo, L. J., Yu, C., … Fan, H. Y. (2013). Death domain-associated protein DAXX promotes ovarian cancer development and chemoresistance. Journal of Biological Chemistry, 288(19), 13620–13630. https://doi.org/10.1074/jbc.M112.446369
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