Focusing the temporally interfering electric fields in non-invasive deep brain stimulation

Abstract

A new design of non-invasive deep bring stimulation system is presented that works based on temporally interfering (TI) electrical fields and high-spatial resolution. The proposed system exploits an increased number of exciting electrical current sources placed around the head transracially to adjust the area and position of the desired region for brain deep neural activation. Only two operational frequencies are used. It is shown that the previously reported TI method can be effectively and systematically extended to focus the amplitude-modulated electric field on the desired location. Results demonstrate that by increasing the number of exciting sources to 40, the spatial resolution of the proposed system can be decreased at least by a factor of 5.8.