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Bioassays for itraconazole blood levels: An interlaboratory collaborative study

Journal of Antimicrobial Chemotherapy (1999) 43(5) 723-727
DOI: 10.1093/jac/43.5.723
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Abstract

Duplicate bioassays for itraconazole and hydroxy-itraconazole were run with 30 serum samples in five laboratories, each using a different method. Both itraconazole and hydroxy-itraconazole were used as standards. Despite quantitative variations, the results of the bioassays correlated sufficiently to indicate the relative level of antifungal activity in the test samples.

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Odds, F. C., Dupont, B., Rinaldi, M. G., Stevens, D. A., Warnock, D. W., & Woestenborghs, R. (1999). Bioassays for itraconazole blood levels: An interlaboratory collaborative study. Journal of Antimicrobial Chemotherapy, 43(5), 723–727. https://doi.org/10.1093/jac/43.5.723

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