It was established that the alkylation of 2-phenylaminothiazoline with substituted phenacyl bromides proceeds at the exocyclic nitrogen atom with the formation of 5-aryl-7-phenyl-2,3-dihydroimidazo[2,1-b]thiazolium bromides. In order to confirm the structure of the last, the reductive desulfurization of one of them (Ar = p-chlorophenyl) was accomplished using Raney nickel. It was shown that dequaternization of the resulting 1-phenyl-3-ethyl-4-(p-chlorophenyl)imidazolium bromide to 1-phenyl-4-(p-chlorophenyl)imidazole, identical to the sample obtained by direct synthesis, thereby occurs. ©1997 Plenum Publishing Corporation.
CITATION STYLE
Demchenko, A. M., Chumakov, V. A., Krasovskii, A. N., Pirozhenko, V. V., & Lozinskii, M. O. (1997). On the reaction of 2-phenylaminothiazoline with α-halogenoketones. Chemistry of Heterocyclic Compounds, 33(6), 724–727. https://doi.org/10.1007/BF02291807
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